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L-citrulline boosts nitric oxide production in the body. Nitric oxide helps your arteries relax and work better, which improves blood flow throughout your body. This may be helpful for treating or preventing some diseases.
There is some evidence to suggest the supplement could possibly help lower blood pressure in people with elevated blood pressure. Elevated blood pressure raises your risk for high blood pressure and heart disease. Definitions for blood pressure levels are:
L-citrulline supplements may ease symptoms of mild-to-moderate erectile dysfunction (ED). Scientists say L-citrulline does not work as well as ED drugs. However, it appears to be a safe option.
Animal studies suggest L-citrulline might also help people with blood vessel problems such as slow wound healing due to diabetes.
Watermelon is the main food source of L-citrulline. The NIHTrusted Source notes that researchers have found that one cup of diced seedless watermelon contains about 365 milligrams of L-citrulline.
L-citrulline concentration can depend on the specific type of watermelon. Research from 2019 notes that L-citrulline levels are high in the Crimson Sweet and Dixielee varieties of watermelon.
Other foods have much lower levels of L-citrulline than watermelon. Some examples of other foods containing L-citrulline include: