High Quality Eucommia Leaves/ Bark Extract Powder

• Packaging Material: Plastic
• Storage Method: Normal
• Shelf Life: >12 Months
• Resource: Natural
• The content of active substances: ＞90%
• Transport Package: 20kg Carton
• Model NO.: food grade
• Specification: Powder
• Trademark: Faithful
• Origin: China
• Production Capacity: 20tons

Product Description

What is Eucommia Leaves Extract  ?

Medicinal herb plants have been used to treat various human diseases in China for thousands of years, and are widely used in cosmetics, foods, and animal husbandry with their function and composition being defined in recent years. Phytochemicals, such as polyphenols, terpenes, and flavonoids are considered bioactive compounds with multiple biological effects including antioxidant, anti-inflammatory, antimicrobial, and anti-tumor. With the prohibition of using antibiotics in feed, plant extracts have been expected to replace antibiotics and thus become a hot spot in animal nutrition research. Earlier, various herbs have been proven to attenuate oxidative stress and improve meat quality in poultry. Eucommia ulmoides, a plant belonging to the monotypic family Eucommiaceae, is one of the oldest tonics in Chinese traditional medicine and is widely distributed in East Asian countries, including China, Korea, and Japan. Although various bioactive components, such as lignans, iridoids, phenolics, steroids, terpenoids, and flavonoids have been identified in Eucommia ulmoides, phenolics and flavonoids, such as chlorogenic acid, protocatechuic acid, and quercetin are considered the main active components in leaves. Previous studies have found that Eucommia ulmoides flavones (EUF) could promote growth performance, improve intestinal health, and reduce colonization of coliform bacteria and diarrhea index in weanling piglets. Eucommia ulmoides leaf extract (EULE) has also been reported to improve the carcass traits of growing-finishing pigs and exert a lipid-lowering effect by activating the pathway and regulating mRNA expression levels related to lipid metabolism. In the diquat-induced oxidative stress piglet model, the dietary supplementation of EUF could increase the protein expression of nuclear Nrf2 and Keap1, and improve the antioxidant capacity of piglets. Although the antioxidant effect of EULE has been reported in pigs, the effect of EULE on broiler chickens, which can be easily affected by oxidative stress, has been rarely reported. The present study attempted to investigate the effects of EULE on oxidative stress, growth performance, and meat quality of broilers, in order to provide references for the usage of EULE as a natural feed additive in broilers.

 

The benefits of our Eucommia Leaves Extract
 

Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider. No supplement is intended to treat, cure, or prevent disease.
The herb, also known as du zhong, is a rich source of antioxidants, lignans, and isoflavonoids-naturally occurring chemicals with hormone-like effects. Eucommia has been used and may be marketed for various uses, including sexual dysfunction, cancer, metabolic syndrome, neurological diseases, and more. However, most research is limited to animal testing and small clinical trials.
One clinical trial evaluated the effect of eucommia on high blood pressure. Most of the remaining research has been done on animals.
Since there is not enough research on eucommia, there are no current recommendations for using eucommia. Research on using eucommia for high blood pressure is included here as it was the only clinical trial found on eucommia in humans.

A small study suggested that eucommina may help lower high blood pressure (hypertension).
For the study, 30 healthy adults took 1 gram (g) of eucommia three times daily for two weeks. At the study's end, the herb was shown to lower blood pressure by an average of 7.5/3.9 millimeters of mercury (mmHg) compared with the control group.
Another study included 24 healthy adults randomized to take 500 milligrams of eucommia extract three times daily for eight weeks. No toxicity or difference in blood pressure was found between the group taking eucommia and the control group in the study.
Additional research on humans is needed to validate these findings.
A meta-analysis of TCM for high blood pressure found that the addition of eucommia combined with traditional medicine was safe, effective, and superior compared to traditional medicine alone.
 

The application of Eucommia Leaves Extract

In the last decade, incidentally, in studies of the anti-hypertensive activities of E. ulmoides, it was discovered that lignans isolated from the bark were able to antagonize the expression of aldose reductase (AR) (300 mg/kg into SHRs), similarly to epalrestat (100 mg/kg), and thus exhibiting effects of against hypertensive vascular remodeling or against hypertensive renal injury. AR is a multifunctional enzyme that reduces aldehydes. The correlation between AR and cardiovascular diseases particularly in the diabetic context has been summarized in an excellent review in 2010. Overall, AR is implicated in excess smooth muscle cell (SMC) growth, and its inhibition manifested as an amelioration of diabetes cardiac diseases and ischemia/reperfusion (I/R)-injured hearts. Although there is still a deficiency of critical evidence that E. ulmoides lignans can act as an AR antagonist to improve cardiovascular disease, it is still a promising candidate for the treatment of diabetic heart disease or I/R-injured hearts.
Comparing to E. ulmoides extracts or active fraction groups, the individual active components of E. ulmoides have been more intensively studied in the treatment of cardiac diseases, involving cardiac hypertrophy, cardiac fibrosis and cardiac remodelling etc., and their associated mechanisms over the past year. For instance, both in vivo and in vitro, aucubin has been found protecting against pressure overload-induced cardiac remodelling via β3-AR-nNOS cascades and it has been found protecting against myocardial infarction-induced cardiac remodeling via nNOS/NO-regulated oxidative stress. Meanwhile, geniposide has been revealed protecting against obesity-related cardiac injury. However, these effects have not yet been reported for E. ulmoides extracts or active fraction groups and needed further investigation to corroborate.

 

Our manufacturer of Eucommia Leaves Extract